Blar i forfatter "Hølvold, Linn Benjaminsen"

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    • Immunostimulants connecting innate and adaptive immunity in Atlantic salmon (Salmo salar) 

      Hølvold, Linn Benjaminsen (Master thesis; Mastergradsoppgave, 2007-11-15)
      The use of immunostimulants in fish farming has received increased attention due to the discovery of Toll-like receptors (TLRs) and pattern recognition receptors (PRRs). These receptors have been found to bind to highly conserved motifs on the surface of pathogens, known as pathogen associated molecular patterns. Most of the studied PAMPs activate antigen presenting cells (APCs) together with naïve ...

    • PLGA (poly(D,L-lactic-co-glycolic)acid) particles as DNA carriers in Atlantic salmon (Salmo salar L.) 

      Hølvold, Linn Benjaminsen (Doctoral thesis; Doktorgradsavhandling, 2013-04-25)
      Adjuvanter benyttes for å styrke/bedre immunresponsen ved vaksinering. PLGA (poly(lactic-co-glycolic)acid) er en biologisk nedbrytbar polymer som innehar adjuvantegenskaper når den benyttes i form av partikler. Som vaksinebærere kan partikler beskytte mot nedbryting, stimulere inflammatoriske immunresponser og initiere adaptive immunresponser. Partikler er også vist å gi økt opptak i ulike celletyper. ...

    • Strategies and hurdles using DNA vaccines to fish 

      Hølvold, Linn Benjaminsen; Myhr, Anne Ingeborg; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Transgene and immune gene expression following intramuscular injection of Atlantic salmon (Salmo salar L.) with DNA-releasing PLGA nano- and microparticles 

      Hølvold, Linn Benjaminsen; Fredriksen, Børge Nilsen; Bøgwald, Jarl; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      The use of poly-(D,L-lactic-co-glycolic) acid (PLGA) particles as carriers for DNA delivery has received considerable attention in mammalian studies. DNA vaccination of fish has been shown to elicit durable transgene expression, but no reports exist on intramuscular administration of PLGA-encapsulated plasmid DNA (pDNA). We injected Atlantic salmon (Salmo salar L.) intramuscularly with a plasmid ...